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IP Archives of Cytology and Histopathology Research


Retrospective histopathological analysis of cervical cancer: Our experience


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Author Details: Lakshmi V, Prakash H Muddegowda, Jyothi B Lingegowda, Konapur PG, Subramanian PM, Thamilselvi R

Volume : 1

Issue : 1

Online ISSN : 2456-9267

Print ISSN : 2581-5725

Article First Page : 28

Article End Page : 31


Abstract

Introduction: Cervical cancer is a malignant neoplasm arising from the uterine cervix. One of the most common symptoms of cervical cancer is abnormal vaginal bleeding, but in some cases there may be no obvious symptoms until the cancer has progressed to an advanced stage. Treatment usually consists of surgery in early stages, and chemotherapy and /or radiotherapy in more advanced stages of the disease.      
Materials and Methods: This retrospective study of histomorphological patterns of cervical lesions was done over a period of 5 years (2008 to 2013). Totally 795 cervical biopsies were received, amongst which 618 biopsies were chronic cervicitis, 95 showed varying degrees of dysplasia’s and 82 cases were malignancies. These cases were further correlated with clinical presentations.
Results: The commonest age group in the malignant cases (18 years to 80 years) were 4th and 5th decade with history of bleeding per vagina being the commonest clinical presentation. Squamous cell carcinoma was the commonest variant.
Conclusion: Histopathological patterns of malignancies needs to be sub-typed further along with special stains, immunohistochemistry and molecular studies, as the treatment modalities and prognosis largely varies with each type of lesion.

Keywords
: Cervix, carcinoma, Histomorphological