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IP Archives of Cytology and Histopathology Research


Psoriasis and significance of clinicopathological correlation in a tertiary care hospital


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Author Details: Kalpana Kumari M.K.

Volume : 2

Issue : 2

Online ISSN : 2456-9267

Print ISSN : 2581-5725

Article First Page : 23

Article End Page : 26


Abstract

Introduction: Psoriasis affects about 0.1-3% of world’s population and causes significant morbidity. The clinical presentation can be variable and often makes clinical diagnosis difficult. Skin biopsies of these patients submitted to histopathology with clinical information and differential diagnosis and pathologist ability to identify the reaction pattern and histomorphological features, is key to better patient care.
Objective: To study histomorphological features of psoriasis of skin and to assess clinicopathological correlation.
Material and Methods: This study was done on 50 consecutive cases of patients of psoriasis in department of pathology of a tertiary care hospital. Detailed study of histomorphological features was conducted.
Results: Psoriasis accounted for 4% of the total skin biopsies received in the department of pathology. The male to female ratio was 1.2:1. In this study maximum number of cases occurred in the age group of 21-50yrs. Histopathological finding such as dilated capillaries, lymphocytic infiltrate and parakeratosis was seen in 100% cases.
Conclusion: There is a definite overlap between morphology and distribution of lesions leading to diagnostic dilemmas which can be solved by distinct histopathological features and clinical correlation.

Keywords:
Psoriasis, Histopathology, Hyperkeratosis, Parakeratosis, Munro’s microabscess