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IP Archives of Cytology and Histopathology Research

Histomorphological study of changes in heart – An autopsy study

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Article Type : Research Article

Author Details: Shah Saloni N*,Patel Kinara A,Patel Himani B,Bhalodia Jignasa N

Volume : 4

Issue : 2

Online ISSN : 2456-9267

Print ISSN : 2581-5725

Article First Page : 159

Article End Page : 163


Introduction and Objectives:  During the last five decades an increasing trend is seen in incidence of cardiac deaths especially among urban population. As post-mortem analysis of heart is the sole way to study gross and histopathological changes in healthy or diseased heart, an autopsy study of heart was therefore planned to observe various histomorphological changes.
Materials and Methods: A prospective randomized study of 161 autopsies submitted for postmortem analysis was conducted in the Department of Pathology, GMERS Medical College and Civil Hospital, Sola over a period of one year from January 2018 to December 2018. Out of 161 autopsies, specimen of heart was received in 159 autopsies, out of which 7 were autolysed. Hence, 152 specimen of whole heart were included in our study. The specimens of whole heart were examined for gross appearance and microscopic section were studied to observe various histomorphological changes and findings were correlated clinically.
Results and Conclusions: Among sudden deaths, coronary atheroscleorsis was found to be the most common pathogenic factor leading to ischemic heart disease. Also, three vessel involvement was the most common pattern in coronary atherosclerosis. Hence , thorough examination of cardiovascular system is necessary in case of autopsy to reach to cause of death.

Keywords: Autopsy, Coronaries, Heart, Histology, Morphology.

Doi :-https://doi.org/10.18231/j.achr.2019.030