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International Dental Journal of Student Research

Oral leukoplakia: risk of malignant transformation and the importance of surgical excision

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Author Details: Mariem Meddeb, Abdellatif Chokri, Faten Hammedi, Karim Masmoudi, Hajer Hentati, Jamil Selmi

Volume : 4

Issue : 3

Online ISSN : 2278-3784

Print ISSN : 2394-708X

Article First Page : 123

Article End Page : 127


Leukoplakia is the most frequent potentially malignant lesion of the oral mucosa. Its diagnostic and therapeutic present a challenge for dentist. Two clinical cases of oral leukoplakia were reported. The first was a patient using chewed tobacco consulted for a verrucous oral lesion that was surgically completely removed. Histopathological examination of the specimen revealed verrucous carcinoma. The second was a smoker man presenting an oral leukoplakia with fungal infection. After antimycotic treatment and periodic follow up, the clinical signs of candidiasis regressed but the mucosal white patch persisted. A large part of the lesion was removed. Histopathological examination indicated a well-differentiated squamous cell carcinoma.

Leukoplakia, Oral mucosa, Biopsy, Dysplasia, Carcinoma