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Indian Journal of Clinical Anaesthesia


Serum Cholinesterase Levels in Organophosphorous Poisoning Patients on Ventilatory Support


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Author Details: GV Rao, Jyothsna M

Volume : 3

Issue : 1

Online ISSN : 2394-4994

Print ISSN : 2394-4781

Article First Page : 52

Article End Page : 55


Abstract

Introduction: Organophosphorus compounds are anti acetylcholinesterases which exert their toxicity by interfering with the normal function of zetylcholine, an essential neuro - transmitter throughout the autonomic and central nervous system.
Methodology: The study was conducted at the Respiratory Intensive Care Unit of Department of Anaesthesiology. Prior approval for the study and the protocol was obtained from the institution ethical committee. After explaining the possible prognosis in the course of organophosphorus poisoning, consent from a responsible attendant / informant of the patient was obtained before the actual study was initiated.
Results: It’s evident from the above table that maximum number of patients presented with mild poisoning based on the SCE levels (77%) and about 23% had moderate to severe poisoning levels. Conclusion: There was a significant correlation between SCH levels and duration of consumption of OP.

Key words:
Organo Phosphorous poisoning, Serum Cholinesterase, Acetylcholinesterases