Indian Journal of Clinical Anaesthesia

Effect of priming technique and single intubating dose technique on rapid sequence intubation with rocuronium using train of four monitoring

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Article Type : Research Article

Author Details: Anisha Puri,Manisha Bhatt Dwivedi*,Sapna Bansal,Seema Tikku

Volume : 6

Issue : 2

Online ISSN : 2394-4994

Print ISSN : 2394-4781

Article First Page : 215

Article End Page : 219


Aim: Rocuronium bromide has fastest onset time among non- depolarizing muscle relaxants; hence a safe alternative for RSI when the priming principle is used. The primary aim of this study was to compare the intubating conditions with priming technique and single intubating dose technique with rocuronium and to assess the onset time of rocuronium using Train of Four (TOF) monitoring.
Materials and Methods: We conducted a randomized, prospective study in 60 patients of ASA I and II in age group of 20-50 years posted for surgeries under general anesthesia and divided into two groups of 30 each. In Group I priming was done with 1 ml of normal saline and Intubating dose of rocuronium 0.6mg/kg was given. In group II priming was done with 1/10th i.e 0.06 mg/kg (1ml) of the total intubating dose followed by remaining dose of 0.54 mg/kg. In both the groups intubating doses of rocuronium were diluted to 10 ml of normal saline. TOF stimuli was used to assess the time of onset of intubation and Cooper scoring system was used to compare the intubating conditions.
Results: Patients intubated in the priming group showed a faster onset time (61. 97 sec) than single intubating dose group (114.57) with successful intubation in both the groups. Excellent intubating conditions were seen in 97% patients and good intubating conditions in 3% patients of both the groups.
Conclusion: Both priming technique and single intubating dose technique produces excellent intubating condition in majority (97%) of the patients with priming technique showing rapid onset time compared to single intubating dose technique.

Keywords: Rocuronium, Priming, Time of intubation, Intubating condition.

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