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Indian Journal of Clinical Anatomy and Physiology


Alteration in autonomic reactivity from hypothyroid to euthyroid status


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Author Details: Anjali Nadir Bhat, Sabita Yograj, Rakesh Bahl

Volume : 3

Issue : 3

Online ISSN : 2394-2126

Print ISSN : 2394-2118

Article First Page : 377

Article End Page : 381


Abstract

This study was carried out on 25 hypothyroid patients attending the OPD of Govt. Medical College Jammu before their treatment started and after treatment when they attained euthyroid status. The parameters recorded and the tests used were pulse rate, blood pressure, orthostasis, cold pressor test, mental arithmetic and corrected QT interval [QTc] for assessment of sympathetic reactivity and valsalva ratio, heart rate response, expiratory-inspiratory ratio [E:I ratio], heart rate variability, standing-lying ratio [S:L ratio] and 30:15 ratio for assessment of parasympathetic reactivity. Our findings show significant improvement in parasympathetic reactivity after a hypothyroid subject became euthyroid with L_thyroxine treatment. For sympathetic reactivity only some parameters recorded significant improvement.

Keywords: Autonomic nervous system, Sympathetic reactivity, Parasympathetic reactivity, Hypothyroidism