Indian Journal of Clinical Anatomy and Physiology

Correlation between CFF and HbA1C among type 2 diabetic subjects

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Author Details: R. Niruba, KC Subha, A. Vijayalakshmi

Volume : 4

Issue : 2

Online ISSN : 2394-2126

Print ISSN : 2394-2118

Article First Page : 190

Article End Page : 191


Introduction: Diabetes has become a worldwide epidemic and need to reduce the morbidity due to this disease has become the need of hour. India ranks first in diabetic population and diabetic retinopathy affects third of all diabetic patients and its prevalence increases with the duration of diabetes both in urban and rural areas.(1,2)
So we aimed to correlate Critical flicker fusion frequency (CFF) and HbA1C among the type 2 diabetic subjects. Noninvasive simple method of assessing retinal function was applied.
Study Design: Cross sectional observational study.
Materials and Method: Subjects n= 50 males, Age group 40-50 years. All participants had a sedentary life style, Blood pressure and HbA1C were measured. Subjects with history of epilepsy, neurological diseases, peripheral vascular disease, alcoholics, smokers and any other illness or medications that affects CFF were excluded. CFF was measured using in house built LED based CFF M1model instrument.
Results: Mean age = 46 ±82 years,
Mean SBP = 117± 15mmHg, Mean CFF = 35 ± 3Hertzs,
Mean HbA1C = 6.6 ±.3%. Pearson correlation was applied. CFF correlated negatively with HbA1C with r value of -0.499.
Conclusion: We conclude that increased blood glucose affects the retinal functions and decreases the critical flicker fusion frequency indicating the failure of retina to differentiate the flicker in higher frequencies.

: CFF, HbA1C, Type 2 diabetics