Indian Journal of Clinical Anatomy and Physiology

Heart rate recovery to sub maximal exercise in patients with subclinical hypothyroidism – an observational study

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Author Details: Nagalakshmi Vijaykumar, Vivek P, Shobha C. Nallulwar

Volume : 4

Issue : 2

Online ISSN : 2394-2126

Print ISSN : 2394-2118

Article First Page : 250

Article End Page : 253


Introduction: Exercise intolerance is typical characteristic of the subclinical hypothyroidism.
Purpose: Evaluation of heart rate responses to sub maximal exercise in subclinical hypothyroidism.
Materials and Method: Twenty three subclinical hypothyroids and thirty age, sex and BMI matched euthyroid controls were selected. Sub maximal exercise was performed using Bruce protocol using 75% target heart rate in treadmill. Heart rate recovery to sub maximal exercise was done using ECG lead II.
Results: Compared to Euthyroid controls, Subclinical Hypothyroidism (SCH) show a significant increase in warm up period heart rate. (p=0.05). There is a significant increase in the heart rate during recovery period at both 1st and 2nd minute in SCH when compared to controls. (p=0.03, 0.01), negative correlation exist between TSH level and 1st minute heart rate recovery.
Conclusion: We conclude that subjects with Subclinical hypothyroidism, shows a delayed heart rate recovery in response to a sub maximal exercise.

: Parasympathetic tones, Basal metabolic rate, Physical Exertion, Exercise tolerance, Hypothyroidism