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Indian Journal of Clinical Anatomy and Physiology

The histological study of human fetal spleen

Abstract Full Text PDF


In the present observational study, thirty aborted human fetuses of 13-38 weeks gestational age with no obvious congenital abnormality were obtained. To study the histology of spleen in relation to the gestational age, spleen was procured after dissection of fetuses and slides were prepared with H & E staining. The findings were noted under the light microscope. On looking over the literature on development and the important functions served by the spleen as haemopoeitic and lymphoid organ, the following study was undertaken. In the study, the mean body weight of fetuses was 130.83 at 14th week and 3150gm at the age of 38th week. The average crown rump length of fetuses at 14 weeks was 115mm and was 330mm at 38th week. Histologically, at 13th week of age there were large numbers of cells of irregular shape with large nucleus centrally. Few small thin walled vessels are seen. At 20th week of age, clearcut division of red and white pulp was seen. Our study may be regarded as a preliminary study including some detailed results. The histological findings acquired in our study will be beneficial for the evaluations about the fetal spleen.

Keywords: Human fetus, Spleen, Histology.

Doi No:-10.18231/2394-2126.2018.0060