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Indian Journal of Clinical Anatomy and Physiology


An observation into functional aspects of neutrophils in patients with malignant solid tumors before treatment and after chemotherapy and G CSF administration


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Author Details: Parameshwari K, Madhusudhan U

Volume : 5

Issue : 3

Online ISSN : 2394-2126

Print ISSN : 2394-2118

Article First Page : 340

Article End Page : 343


Abstract

Introduction: Uncontrolled growth of a group of cells is called cancer. Most of the drugs and therapies used in the management of cancer are immune suppressive.
Objective: The present study was undertaken to observe the functional aspects of neutrophils in patients with malignant solid tumors before treatment and after chemotherapy and G CSF Administration.
Materials and Methods: A total of 30 adult male and female patients who were newly diagnosed with malignant tumors were included as cases. 30 normal age and gender matched individuals were included as cases. Collection of blood was performed as per standard guidelines.
Results: There was a significant (P value<0> Conclusion: Our results are in accordance with earlier studies as we have observed positive impact on neutrophil percentage followed by the intervention. We recommend further detailed studies in this area with involvement of more parameters and large population.

Keywords: Malignant tumors, Chemotherapy, Neutrophil.

Doi :-https://doi.org/10.18231/2394-2126.2018.0078