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International Journal of Clinical Biochemistry and Research


A study on glucose tolerance test in young sputum positive tuberculosis patients


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Author Details: Ushanagadevi C.S., Beenakumari K., Moses.K. Daniel, M.R. Laveesh

Volume : 3

Issue : 1

Online ISSN : 2394-6377

Print ISSN : 2394-6369

Article First Page : 82

Article End Page : 88


Abstract

Introduction: Diabetes mellitus and Tuberculosis are among the most prevalent chronic diseases in India. The correlation and coexistence of both the diseases are very important as they influence the clinical course and therapeutics of each other.
Material and Methods: It was a cross sectional study conducted on 122 patients of newly diagnosed young sputum positive tuberculosis patients visiting a tertiary care hospital. Selected socio-demographic, laboratory and radiological data were elicited from these patients and recorded in the proforma. After GTT, patients were grouped according to ADA 2003 recommendations of hyperglycaemia into Normal, IFG, IGT and DM was done.
Observation and results: The total number of patients with abnormal blood sugar values (IFG, + IGT + DM) account for 53.28% of the study group. IGT is significantly high in TB population (31%) when compared to (14%) that in normal population and p value is significant <0.05.On radiological examination, a total of 61% of the study group shows upper zone involvement and the lesions were mostly infiltrates. There was no statistical correlation between IGT or DM and increased BMI.IGT and DM was more among urban population and this was statistically significant.
Conclusions: In view of the increased prevalence of diabetes mellitus in tuberculosis population it is suggested that all tuberculosis patients should be evaluated clinically and biochemically for diabetes mellitus as detection and control of diabetes mellitus will help to achieve better tuberculosis control.

Keywords:
ADA: American Diabetic Association, IFG: Impaired Fasting Glycaemia, IGT: Impaired Glucose tolerance, OGTT: Oral Glucose Tolerance test, DM; Diabetes Mellitus