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International Journal of Clinical Biochemistry and Research


Diabetes Accelerates Age- Related Lipid Profile Disturbances in Cardiovascular Complications


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Author Details: Md. Ezaz Zafar, Faizur Rahman, K. R. Prasad, M Nehal

Volume : 3

Issue : 2

Online ISSN : 2394-6377

Print ISSN : 2394-6369

Article First Page : 154

Article End Page : 158


Abstract

Cardio Vascular Complications (CVC) are predominant problems both in ageing and diabetes. The present study focuses on the effect of human ageing and diabetes, with special reference to serum lipid profile levels during cardiovascular complications in two age groups namely, 45±5 years and 65±5 years independent of obesity hypertension and nephropathy. The serum samples of study and control group includes estimation of serum total cholesterol, serum triglycerides, HDL-C, LDL-C and VLDL-C. Results shows, that the changes in the levels of lipid parameters follow a near similar trend in the two non-diabetic age groups with cardiovascular complications. Except the HDL-C which decline, total cholesterol, LDL-C, VLDL and triglycerides increases.
In diabetes, however, the said lipid parameters are not so similarly affected in the stated age subjects. One interesting observation is the near similar levels of lipid parameters found in diabetic 45±5 y and non-diabetic 65±5 y age groups with Cardiovascular complications. It is, therefore, suggested that diabetes accelerates age related disturbances in the lipid profile.

Key Words:
Diabetes, Ageing, Lipid profile and CVC