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International Journal of Clinical Biochemistry and Research


Association of Thyroid Dysfunction in Patients withType-2 Diabetes Mellitus


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Author Details: Shreerang Pralhad Kulkarni, Rakesh Mudaraddi, Dhiraj J Trivedi, Pramod S Kamble

Volume : 3

Issue : 2

Online ISSN : 2394-6377

Print ISSN : 2394-6369

Article First Page : 172

Article End Page : 176


Abstract

Background: Diabetes Mellitus is the most common endocrine disorder worldwide. The role of insulin and thyroid hormones appears to be vital in regulating cellular metabolism. Co-existence of thyroid abnormality and diabetes may influence each other in disease process. The aim of the present study is to correlate thyroid disorders among diabetic case group.
Materials and Methods: The present study was done on 350 subjects, which include 175 healthy subjects and 175 type 2 diabetic cases. Thyroid hormones, Blood glucose levels and Glycosylated haemoglobin (HbA1C) were analyzed and results were compared with healthy individuals.
Results: In this study, the thyroid dysfunction was observed in 17.71% of case group. Out of 175 cases the frequency of hypothyroidism and hyperthyroidism is 16% and 1.71% respectively and euthyroid state was 82.29%.
Conclusion: The interrelationship between type 2 diabetes and thyroid disease is found to be significant in this study. By considering this association, regular screening for thyroid function test along with the diabetic profile in diabetics may help in better management of these patients.

Keywords:
Hyperthyroidism, Hyperglycaemia, Subclinical Hypothyroidism, Diabetes Mellitus, Thyroid Dysfunction