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International Journal of Clinical Biochemistry and Research


Levels of microalbuminuria in prediction of pre-eclampsia: A hospital based study


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Author Details: Inder Pal Kaur, Ashish Shukla, Sukanya Gangopadhyay, Akash Gupta, Gautam Sarkar

Volume : 3

Issue : 4

Online ISSN : 2394-6377

Print ISSN : 2394-6369

Article First Page : 354

Article End Page : 356


Abstract

Introduction: Pre-eclampsia (PE) is defined as the new onset of hypertension and proteinuria during the second half of pregnancy. In the Indian scenario, it accounts for 44.44% of all cases of hypertensive disorders of pregnancy. Microalbuminuria is one the classic signs of pre-eclampsia.
The aim of the study was to determine microalbuminuria as predictor of pre-eclampsia.
Methods: A total of 145 pregnant women in their second trimester of pregnancy were included in the study. From all these subjects, clean catch morning urine sample (5ml) was collected in a sterile container. Urinary Creatinine and urinary microalbumin was estimated by kit based method on Vitros Fusion 5.1 FS fully automated analyzer from Ortho Clinical Diagnostic USA. The statistical significance of difference between mean values was assessed by Student’s unpaired t-test.
Result: Pregnant women who developed pre-eclamsia were having significantly higher micro albumin level and Albumin Creatinine Ratio as compared to normotensive pregnant women.
Conclusion: To determine microalbuminuria as predictor of pre-eclampsia, further detailed study is required in large group of population.

Keyword
: Pre-eclampsia, Microalbuminuria, Albumin Creatinine Ratio, BP, Pregnancy