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International Journal of Clinical Biochemistry and Research


A comparative study of electrolyte imbalances in controlled and uncontrolled diabetes mellitus


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Author Details: Deepti GN, Sumina Cherian, K. Lakshmi

Volume : 4

Issue : 1

Online ISSN : 2394-6377

Print ISSN : 2394-6369

Article First Page : 22

Article End Page : 24


Abstract

Objective: Our aim is to study the pattern of electrolyte imbalances in patients with diabetes mellitus and to compare the results among controlled and uncontrolled diabetes mellitus and also to find out the correlation between electrolyte levels and HbA1c.
Methods: This Cross-sectional study was conducted in a tertiary care hospital in Kerala for a period of one month. Blood samples were collected from 77 Diabetic subjects and 15 controls who were age and sex matched. Samples were analysed for HbA1c, sodium, potassium, chloride and magnesium levels.
Results: In our present study, there was significant lowering of magnesium levels in diabetes patients. While performing Pearson correlation between HbA1c and electrolytes, there was significant negative correlation of HbA1c with magnesium. Overall analysis of our study showed that there is no significant variation in sodium, potassium & chloride levels in diabetes mellitus patients compared to non-diabetics. Variation in magnesium levels were pronounced in uncontrolled diabetes mellitus patients compared to diabetes mellitus patients whose glycemic levels were under control.
Conclusion: Magnesium imbalance is common in diabetic people in our area, compared to other electrolyte imbalances. Diabetic people should be screened for electrolyte imbalances and steps must be taken to prevent their consequences.

Keywords:
Electrolyte imbalance, diabetes, HbA1c, Sodium, Potassium, Chloride, Magnesium