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International Journal of Clinical Biochemistry and Research


Dyslipidemia correlating with reduced glomerular filtration rate in apparently healthy individuals


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Author Details: V. Malarkodi, M. Malathi

Volume : 4

Issue : 2

Online ISSN : 2394-6377

Print ISSN : 2394-6369

Article First Page : 198

Article End Page : 200


Abstract

There are many studies relating the renal dysfunction with dyslipidemia. This study intended to assess the correlation of estimated glomerular filtration rate (eGFR) with the lipid levels in apparently healthy individuals. A total of 211 people with normal serum creatinine and no previous history of cardiovascular disease or renal disease were selected. Hypercholesterolemia and hypertriglyceridemia are now being reported as risk factors for progression of renal disease. Recently it has been studied that a rise in apolipoprotein B rich lipoproteins to be associated with decline in renal function. In this study there was a significant negative correlation of Low Density Lipoprotein (LDL) and total cholesterol with e GFR. There was a positive correlation with High Density Lipoprotein (HDL) and negative association with non HDL cholesterol. However larger cohort studies are required to establish dyslipidemia as a causative factor for renal dysfunction.

Keywords:
eGFR, Hypercholesterolemia, Dyslipidemia