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International Journal of Clinical Biochemistry and Research


A comparative study of glucose concentration determined from venous plasma sample and capillary blood sample


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Author Details: Ayaz Khurram Mallick, Marya Ahsan

Volume : 4

Issue : 3

Online ISSN : 2394-6377

Print ISSN : 2394-6369

Article First Page : 220

Article End Page : 224


Abstract

Context: Self-monitoring of glucose levels with a hand held glucometer is very popular among the diabetic patients and doctors as it is less traumatic and gives instant results. Capillary blood samples are commonly used for self-monitoring in comparison to venous plasma sample which are used in the diagnostic laboratories.
Aims: This study was done to compare the glucose levels of a capillary blood sample determined by a glucometer with the glucose level determined by Glucose Oxidase Peroxidase (GOD-POD) method using a venous plasma sample.
Setting and Design: This experimental study was carried out at Rohilkhand Medical College and Hospital.
Methods and Material: Two hundred patients were randomly selected for the study. Their venous blood samples were collected in a fluoride containing blood collection tube. The plasma obtained was subjected to GOD-POD test. Simultaneously their capillary blood glucose was also determined by a glucometer.
Statistical analysis used: The data collected was analyzed using SPSS 17.0 version. Data was expressed as mean ± SD. Significance of mean was analyzed using paired t test. P value < 0.05 was considered significant.
Result: Glucose levels determined by a glucometer and GOD-POD method showed very good correlation (r=0.958; p<0.001). However, at very high and low glucose levels, the glucometer significantly under estimated (p=0.014) and over-estimated (p<0.001) the glucose levels respectively.
Conclusion: Although glucometers are effective for routine monitoring of glucose levels, they should be used cautiously in emergency conditions.

Keywords:
Glucose levels, GOD-POD method, Glucometer

Doi No:-10.18231