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International Journal of Clinical Biochemistry and Research


Evaluation of microalbuminuria in non-diabetic and non-hypertensive patients with acute myocardial infarction


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Author Details: Dharmesh Gamit, Bhavika Vanani, Chintan Patel, Avanish Mishra, Ankur Patel

Volume : 4

Issue : 3

Online ISSN : 2394-6377

Print ISSN : 2394-6369

Article First Page : 225

Article End Page : 228


Abstract

Introduction: Microalbuminuria is defined as the excretion of 30to 300mg of albumin per day in urine. It is frequently present and a known cardiovascular risk indicator in diabetic populations, in hypertensive and general populations. Elevation of microalbuminuria level is emerging as risk factors in myocardial infarction.
Aim and Objectives: To explicit the relationship between microalbuminuria and acute myocardial infarction as prognostic indicator of cardiovascular 
morbidity and mortality.
Materials and Method:
Study design: A cross sectional hospital based study.
Study subjects: 120 non-diabetic and non-hypertensive patients of acute myocardial infarction, after taking the consents.
Study duration: August 2012 to November 2014
Study setting: Intensive Care Unit, Gujarat Medical Education and Research Society College, Civil hospital, Valsad, Gujarat. Study materials: Microalbuminuria was determined by immunoturbidimeteric method. Serum glucose and Serum creatinine were measured by GOD-POD end point &Modified Jaffe’s method respectively.
Results: 120 patients of myocardial infarction with a mean age of 51.32 ± 11.25years with range of 30 to 70 years. In majority 79 (65.8%) of the cases found with microalbuminuria while 41(34.2%) with normal buminuria 79 (65.8%) cases in which presence of microalbuminuria was found and the association between microalbuminuria & mortality in patients with MI shows that, those were died i.e. 33 (27.5%) in which microalbuminuria was present in around 20 (60%) cases.
Conclusion: Association between microalbuminuria and myocardial infarction suggests that microalbuminuria has additional value as a prognostic marker in absence of risk factors like Diabetes and Hypertension.

Keywords:
Coronary heart disease, Myocardial infarction, Micro-albuminuria