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International Journal of Clinical Biochemistry and Research

A Comparative Study on Plasma Fibrinogen and hs-CRP in Metabolic Syndrome

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Author Details: Shifa K, Jithesh T.K., Parwathi K Warrior, Liji K

Volume : 2

Issue : 3

Online ISSN : 2394-6377

Print ISSN : 2394-6369

Article First Page : 162

Article End Page : 165


Back ground &Objective: Metabolic syndrome (MS) comprises a group of various metabolic abnormalities related with high risk of cardiovascular disease. The relationship of plasma fibrinogen and hs-CRP levels with MS remains inconclusive. The aim of this study was to assess the correlation of fibrinogen and hs-CRP levels in metabolic syndrome.
Methods: It is a case control study. Detailed clinical, epidemiological and anthropometric characteristics were recorded using pro-forma. 5ml fasting venous blood collected from all the subjects after getting the informed consent.The blood samples thus obtained was used for studies including Lipid profile, hs-CRP, blood sugar and plasma fibrinogen.
Results: Fibrinogen and hs-CRP levels show significant increase in MS group. But there is no significant correlation between fibrinogen and hs-CRP levels.
Interpretation & Conclusion: Hyper fibrinogenemia and an increase in hs-CRP level in the test population explain the increased cardiovascular risk. Plasma determination of these inflammatory biomarkers might have a role in predicting the severity of metabolic syndrome.
Key words: Metabolic syndrome, Fibrinogen, hs-CRP