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Indian Journal of Clinical and Experimental Ophthalmology


Evaluation of endothelial cell density and central corneal thickness in cases of pseudoexfoliation


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Author Details: Nishat Sultana, Apoorva Mithranand, Vinuta Mohan Kulkarni

Volume : 3

Issue : 2

Online ISSN : 2395-1451

Print ISSN : 2395-1443

Article First Page : 154

Article End Page : 158


Abstract

Background: Aim of the study is to evaluate endothelial cell density and central corneal thickness in cases of pseudoexfoliation admitted for cataract surgery in tertiary care hospital using specular microscopy.
Materials and Methods: Total of 30 cases were studied prospectively in a period of 10 months during march,2016 to jan,2017 to evaluate the endothelial cell density and CCT using specular microscopy with detailed history and ocular examination.
Result: In our study of 30 cases, it was shown no gender predilection and bilaterality was seen in 83%.80% of cases had endothelial cell density less than 2500cells/µm on specular microscopy. 93% of cases had CCT less than 545µm which is grossly significant as seen in previous studies.
Conclusion: Pseudo exfoliative syndrome presents challenges to the operating surgeon that require careful pre-operative evaluation. Our study showed that these cases have significantly lower endothelial cell density and increased risk of corneal decompensation after intra ocular surgeries. These pseudo exfoliative cases also have significantly low central corneal thickness which may under estimate the IOP reading and overlook an early glaucomatous damage. Thus evaluation of endothelial cell density and central corneal thickness becomes an imperative pre-operative step in cases of pseudo exfoliation.

Keywords:
Central corneal thickness, Endothelial cell density, Pseudoexfoliation, Specular microscopy