IP Indian Journal of Immunology and Respiratory Medicine


Socioeconomic and clinical analysis of 50 Multi-drug resistant Tuberculosis cases in Rajkot district of Gujarat, India


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Author Details: Rajesh Pimpaldara, K.G. Vithlani, Manisha Vasava, Rakesh Pimpaldara

Volume : 2

Issue : 1

Online ISSN : 2581-4222

Print ISSN : 2581-4214

Article First Page : 16

Article End Page : 20


Abstract

Background: This study was conducted to analyse the socioeconomic and clinical profile of MDR TB patients in Rajkot to deal with this growing threat.
Methodology: Total of 50 cases 0f MDR TB were analysed retrospectively in a period of 2 years during August 2013 to august 2015 to study various variables like age, sex, socioeconomic status, residence, occupation and clinical profile.
Results: Most of the patients with MDR TB were in weight band of 26-45 kg and 46-70 kg and in age group of 21-40 and 41-60. 64% were male and 36% were female showing M:F ratio 1.7:1. The average BMI of patients in this study is 17.42. Most of patients were from lower (60%) and middle (36%) socioeconomic status. Almost all patients had fever, anorexia and weight loss. 26% Patients were category-I failure, 30% category-II failure, 16% defaulter and 28% were from relapse group. 36% had only Rifampicin R resistance while 64% had both R and Isoniazid (H) resistance. At the end of 6 months of treatment; 78% had culture conversion, 22% had culture non-conversion, 16% patients were defaulter, 8% were died and 76% were on treatment.
Conclusions: Study revealed that lack of education, poor life style, poor nutrition, adverse effects of drugs, and absence of follow up visits led to non-compliance. So there is a great need of patient counselling and follow-up visits to improve their quality of life and safety of other people around.

Keywords:
DST; MDR TB; Non-compliance; Socioeconomic factor; XDR-TB