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IP International Journal of Medical Microbiology and Tropical Diseases


Isolation & study of multidrug resistant Acinetobacter from various clinical samples in a tertiary care hospital


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Author Details: S.V. Wankhede, D.P. Ghadage, T.R. Patil, A.V. Bhore

Volume : 2

Issue : 2

Online ISSN : 2581-4761

Print ISSN : 2581-4753

Article First Page : 56

Article End Page : 59


Abstract

Introduction: Nosocomial infections with Acinetobacter are being increasingly reported worldwide from debilitated& Critical care patients. Multidrug resistance among Acinetobacter are now a major cause of concern.
So the study was conducted to know prevalence & antimicrobial resistance pattern of Acinetobacter species in our area.
Materials & Methods: A total of 100 non-duplicate clinical specimens were processed for Acinetobacter by the routine microbiological procedures. Antimicrobial susceptibility testing was performed as per CLSI guidelines.
Result: Acinetobacter species were isolated from 9% of clinical samples. The higher percentage of isolates were from Pus 7(20%) followed by urine 1(4%) and 1(3%) from Blood. We found Highest isolates were from ICU -7(77.78%) followed by wards 2(22.22%). No isolates were found from Outpatient (OPD).
77% of our isolates showed resistance to drugs piperacillin-tazobactam and ceftriaxone while lower resistance was noted to ciprofloxacin &tetracyclines (33% respectively).
Resistance pattern for other drugs was co-trimaxazole (66%), gentamycin & piperacillin (55% respectively), amikacin, ofloxacin & imepenem - 44%. Interesting finding in our study was 11% of our isolated were sensitive to all the tested antimicrobials whereas 22% isolates were resistant to all the tested antimicrobials.
Conclusion: 22% of our isolates showed resistant to all the tested antimicrobials. Thus judicial use of antimicrobials & adopting strict infection control policies will be useful.

Key words
: Multidrug resistance, Morbidity & Mortality, Acinetobacterspp, ICU & debilitated patients, Antimicrobial policy, Infection control