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IP International Journal of Medical Microbiology and Tropical Diseases


Seroprevalence of toxoplasmosis in antenatal women with bad obstetric history attending antenatal OPD in a tertiary hospital in Assam


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Author Details: Vaishali Sarma, Naba Kumar Hazarika

Volume : 2

Issue : 4

Online ISSN : 2581-4761

Print ISSN : 2581-4753

Article First Page : 125

Article End Page : 130


Abstract

Background: Toxoplasmosis has long since been incriminated with pregnancy wastage. In India, studies clearly show the rise in toxoplasma infection over last few decades. The present study is an effort to revisit the trend of maternal toxoplasmosis in this part of the country presently.
Material and Method: Serum samples collected over one year from 90 pregnant women were tested for IgG and IgM antibodies against Toxoplasma gondii by ELISA. 60 pregnant women with history of two or more foetal wastage in the form of abortions, premature labour, stillbirth, congenitally malformed fetus, intrauterine growth retardation, intra uterine death or neonatal death comprised the study group. Control group consisted of 30 healthy pregnant women with two or more normal pregnancies without any bad obstetric history (BOH).
Results: Overall prevalence of toxoplasmosis based on IgG seropositivity was 38.9% demonstrating very high prevalence of maternal toxoplasmosis. Positivity was higher in the study group with higher positivity among asymptomatic study cases.
Conclusions: High prevalence of toxoplasmosis found among pregnant women in the study is clearly indicative of toxoplasma endemicity in this region. Accurate and timely diagnosis is vital for prompt institution of therapy and hence there is a genuine role of screening pregnant women for Toxoplasmosis in this part of India.

Keywords:
Toxoplasmosis, ELISA, Pregnancy Wastage