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Indian Journal of Microbiology Research


A study on the prevalence of Methicillin Resistant Staphylococcus aureus(MRSA) isolates from various clinical samples in a tertiary care hospital


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Author Details: Vijayalakshmi. Arumugam, Dillirani. Vedachalam, Malathi. Murugesan, Ananthakrishnan. Parthasarathy

Volume : 3

Issue : 1

Online ISSN : 2394-5478

Print ISSN : 2394-546X

Article First Page : 65

Article End Page : 68


Abstract

Background: Staphylococcus aureus is the most common cause of hospital and community acquired infections. The increasing prevalence of Methicillin Resistant Staphylococcus aureus (MRSA) has led to the widespread usage of Vancomycin which in turn leads to the emergence of resistance to glycopeptides antibiotics. Hence this study is aimed at analyzing the prevalence of Methicillin Resistant Staphylococcus aureus isolates from various clinical specimens.
Methodology: A retrospective study was conducted over a period of one year in a tertiary care hospital from various clinical samples received during the study period. Staphylococcus aureus isolates were identified by phenotypic methods and MRSA isolates were identified by Cefoxitin disk diffusion method as per CLSI guidelines.
Results: Out of 10842 different types of samples processed, 212 isolates of Staphylococcus aureus were identified. Among them 59 (27.83%) were found to be Methicillin Resistant Staphylococcus aureus (MRSA) and 153 (72.17%) were found to be Methicillin Sensitive Staphylococcus aureus (MSSA).
Conclusion: The above study concludes that it is a must to implement appropriate diagnostic methodology for isolating MRSA strains and also to ensure strict antibiotic policy in all the health care institutions with precautionary measures before starting the patient on Vancomycin.

Keywords:
Staphylococcus aureus, MRSA, Vancomycin, MSSA, CLSI