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Indian Journal of Microbiology Research


Bacteriological profile and antimicrobial susceptibility patterns of organisms responsible for blood stream infections


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Author Details: Qursheed Sultana, Humera Ansari, M.A. Wahab Ansari

Volume : 3

Issue : 2

Online ISSN : 2394-5478

Print ISSN : 2394-546X

Article First Page : 113

Article End Page : 117


Abstract

Background: Blood stream infections (BSI) are an important cause of morbidity and mortality. An assessment of a patient with BSI includes routinely a blood culture. Blood cultures provide us information on the causative organism and their antibiotic susceptibility over the past few decades.
Objective: To identify organisms responsible for Blood stream infections, study their bacteriological profile and antimicrobial susceptibility patterns.
Methods: This study was undertaken to analyze all blood culture reports from January 2015-July 2015 at a tertiary care hospital in Hyderabad, India. A total of 485 blood culture reports were analyzed all suspected cases of septicemia.
Results: Best sensitivity of the gram positive isolates were for vancomycin and Tigecycline, both giving 97.67% sensitivity followed by Linezolid at 91.86%.The isolates showed good sensitivity of 77.91% to Teicoplanin and Beta-Lactamase combination showing a sensitivity of 72.09% to cefoperazone sulbactam, 66.28% to Ampicillin-sulbactam and 73.26% to cefepime-tazobactum. Resistance was high to other Beta-lactam antibiotics and the Macrolides.
Conclusion: The study showed a predominance of gram positive organisms as compared to gram negative isolates, most of the isolates were resistant to multiple antibiotics.

Key words:
Staphylococcus aureus, Blood stream infections, Vancomycin