Volume : 4
Issue : 1
Online ISSN : 2394-5478
Print ISSN : 2394-546X
Article First Page : 68
Article End Page : 73
Introduction: One of the most important complications of diabetes mellitus is foot infection. Bacterial spectrum of diabetic foot infections vary greatly. The increasing association of multi-drug resistant (MDR) bacteria in diabetic foot infections further complicates therapy. Hence, we aimed at determining the prevalence of bacteria in diabetic foot ulcers and their anti-biogram.
Materials and Methods: This is a prospective, observational study. A total of 217 infected diabetic wound samples (pus swab/discharge) were collected from patients seen both IP department and OP departments of Vinayaka Mission’s Medical College & Hospital. Antimicrobial resistance pattern was performed, as per standard microbiological procedures including methicillin resistant S. aureus and extended spectrum of beta lactamase (ESBL).
Results: Overall 207 bacteria were isolated. Among them, 122 (58.94%) were Gram negative bacilli and others were Gram positive cocci, 85(41.06). The most common isolate was Pseudomonas (23.67%) followed by Staphylococcus aureus (22.70%), Coagulase negative Staphylococci (15.94%), Klebsiella species (14.97%), Escherichia coli (9.18%). Among 122 Gram negative bacilli, 57 were identified as ESBL producing strains. A total of 47 isolates of Staphylococcus aureus were recorded, 22 were identified as MRSA strains. Majority of Gram negative isolates were susceptible to piperaciillin/tazobactum followed by amikacin. All isolates remained susceptible to cefeperazone/sulbactum and imipenam except non fermenting Gram negative bacilli.
Conclusion: Regular monitoring of bacterial susceptibility patterns helps in guiding clinician to choose apt antibiotic to treat infected diabetic foot. Treatment should be initiated only after performing culture and sensitivity testing. Therefore, the rapid propagation of multi drug resistance can be prevented.
Keywords: Diabetic Foot Infection, ESBL, MRSA, Imipenam, Linezolide