Indian Journal of Microbiology Research


Xpert MTB/RIF – A new gold standard for extrapulmonary Tuberculosis?


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Author Details: Ashish Bahal, H.S. Sidhu, Anurag Khera

Volume : 4

Issue : 1

Online ISSN : 2394-5478

Print ISSN : 2394-546X

Article First Page : 114

Article End Page : 117


Abstract

Background: Tuberculosis infection can develop in the forms of Pulmonary as well as Extra Pulmonary form which are seen as major complications in HIV/AIDS. Tuberculosis is still a diagnostic dilemma in low resource countries. In cases of Extra Pulmonary tuberculosis, the problem is further compounded by presence of low numbers of bacilli in patient sample. We have made an effort to compare the results of microscopy with results of Xpert MTB/ RIF assay in evaluation of Extra Pulmonary samples.
Materials and Methods: 139 consecutive samples from patients suspected to have any form of extra pulmonary tuberculosis were subjected for microscopy with Ziehl Nielsen staining and simultaneous testing for of Xpert MTB/ RIF assay. The results were compared.
Results: Xpert MTB/RIF positivity for MTB observed in 56.12% (78/139) while 61 (43.88%) were negative on Xpert MTB/RIF. Out of 125 ZN smear negative subjects 66 (52.8%) were found to be positive for MTB by Xpert MTB/RIF. Out of 14 ZN smear positive cases, Xpert MTB/RIF negative cases were found to be 2 (14.28%).

Keywords:
Extra Pulmonary Tuberculosis, Xpert MTB/ RIF