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Indian Journal of Microbiology Research


Bacteriological profile and antibiogram of uropathogens among antenatal cases in a Tertiary Care Hospital


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Author Details: Reshmi Gopalakrishnan, B.V. Chandrashekara Murthy

Volume : 4

Issue : 3

Online ISSN : 2394-5478

Print ISSN : 2394-546X

Article First Page : 333

Article End Page : 337


Abstract

Introduction: Urinary tract infection (UTI) is one of the commonest complications occurring during the antenatal period. It can result in adverse outcomes like abortion, premature delivery, low birth weight. Screening of antenatal patients help in early diagnosis of UTI and thus to prevent maternal and fetal morbidity and mortality.
Aims: The present study was carried out:
1.        To determine the prevalence of UTI in pregnant women.
2.        To study the bacteriological profile and antimicrobial susceptibility pattern of the uropathogens.
Materials and Method: 269 antenatal patients who attended the antenatal clinic during the study period January 2015 – December 2016 were included in this study. Mid stream urine sample was collected from these patients. Samples were processed and isolates were identified. Antibiotic susceptibility was recorded as per CLSI guidelines.
Results: The prevalence of UTI among pregnant women was 16.9%. Majority of the culture positive patients belonged to the age group of 25-29 yrs. 91.3% were Gram negative isolates and 8.7% were Gram positive organisms. E.coli was the most common uropathogen. Ampicillin, amoxicillin clavulanic acid, cotrimoxazole were found to be resistant to most of the Gram negative uropathogens. Most of the Gram negative isolates were sensitive to amikacin, nitrofurantoin, ceftriaxone, quinolones. For Gram positive uropathogens, ampicillin can still be safely prescribed as first line antibiotic.
Conclusion: This study reveals the importance of screening of pregnant women for UTI. Increasing resistance observed among the uropathogens emphasizes the need to rationalize the use of antibiotics which would eventually prevent the development of resistant strains.

Keywords:
Urinary tract infections, Pregnancy, Uropathogens, Antibiotic resistance