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Indian Journal of Microbiology Research


Seroprevalence and changing trend of dengue in a tertiary care hospital


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Author Details: Mahesh Kumar S, Pramod N. Sumbrani, Asha B. Patil, Sheethal S, Akshat Vij

Volume : 4

Issue : 4

Online ISSN : 2394-5478

Print ISSN : 2394-546X

Article First Page : 424

Article End Page : 427


Abstract

Introduction: Dengue fever is a seasonal acute febrile arbo-viral illness ranging from asymptomatic infection to dengue fever and the severe dengue haemorrhagic fever dengue shock syndrome. India is one of the seven identified countries in the South-East Asia region regularly reporting dengue fever dengue hemorrhagic fever outbreaks.
Objectives: To identify dengue seropositive patients by NS1 antigen testing and anti-dengue IgM antibody detection by ELISA and correlate the changes in epidemiology.
Materials and Method: Retrospective study done from January 2013 to December 2015 with blood samples tested from clinically suspected cases of dengue virus infection.
Results: A total of 3839 samples were tested. NS1 ELISA detected 196 (5.11%) cases and MAC ELISA registered 488 (12.71%) positives. Maximum number of cases was reported from June to September. Incidence was high in the paediatric age group with an overall male predominance. Mortality rate reported among dengue positive cases during 2013 was 9 (1.35%), 5 (3.12%) during 2014 and 1 (0.65%) during 2015.
Conclusion: Prevalence of dengue seropositive cases was 34.20% in 2013, 19.07% and 14.89% in 2014 and 2015 respectively indicating a relative decline in dengue infection which may be attributable to the increase in awareness and preventive measures taken among the people and health services.

Keywords:
Dengue fever, Dengue haemorrhagic fever, NS1 Ag, IgM, ELISA