Cannabis induced psychosis in patient with traumatic brain injury
The association between TBI (traumatic brain injury) and psychosis remains a subject of debate and controversy. Differentiating patients with psychosis attributable to TBI and from patients with primary psychosis is difficult. Research has found that cannabis use prior to the age of 15 confers the greatest risk, due to the drug’s effect upon the neurodevelopment processes occurring in the adolescent brain. In a study on heavy cannabis users demonstrated that significant dose-related hippocampal volume reductions, though in case of TBI reports varied with severity of TBI to trigger a psychosis in cannabis user. Some studies suggest that individuals who develop a psychosis after TBI had generally sustained moderate to severe head injuries.
In our case patient has long history of bilateral frontal lobe injury, although up to long time he was normal but when he started taking cannabis the symptoms of psychosis occurred. We have presumed that cannabis act as induction in development of psychosis in this case.
Keywords: Psychiatric disorders, Traumatic brain injury, Neuropsychiatry