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IP International Journal of Ocular Oncology and Oculoplasty

Ocular surface squamous neoplasia (OSSN)

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Author Details: Jayasri Krishnaraj, Sagnik Surya Das, Kalaimamani Ezhil Vendhan

Volume : 2

Issue : 1

Online ISSN : 2581-5016

Print ISSN : 2581-5024

Article First Page : 19

Article End Page : 30


OSSN is the third most common conjunctival malignancy worldwide and is commonest in the tropics. It is a tumor of the elderly and is usually misdiagnosed, as it resembles benign conditions like pinguecula and pterygium. We are now equipped with a wide array of investigative modalities ranging from Impression cytology to confocal microscopy. Treatment of choice for OSSN is surgical excision with cryotherapy and may be combined with other modalities like immunotherapy, topical chemotherapeutic agents and radiotherapy. Recently pegylated interferon has shown promising results in management of recurrent OSSN.

Key Words:
Cryotherapy, Human Papilloma Virus, Impression cytology, Interferon, Squamous neoplasia