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International Journal of Pharmaceutical Chemistry and Analysis


Preparation of azadirachta indica alkaline phosphatase loaded egg albumin and bovine serum albumin nanoparticles


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Author Details: Kirti Rani

Volume : 4

Issue : 2

Online ISSN : 2394-2797

Print ISSN : 2394-2789

Article First Page : 43

Article End Page : 45


Abstract

Azadirachta indica is rich source of alkaline phosphatase and alkaline phosphatase are known for their industrial application in food and pharmaceutical industries. The extracted alkaline phosphatase was encapsulated into biochemically active egg albumin and BSA nanoparticles with butanol and glutaraldehyde. Achieved encapsulation was 69% when egg albumin (EA) used and 85% was observed when bovine serum albumin (BSA) was used. Characterization of prepared albumin nanoparticles was done by scanning electron microscopy (SEM). Observed size of enzyme loaded nanoparticles was reported up to 80nm when egg albumin was used and up to 100m when bovine serum albumin was used for encapsulating the Azadirachta indica alkaline phosphatase.

Keywords:
Azadirachta indica, Alkaline phosphatase, Bovine serum albumin, Egg albumin, Encapsulation

Doi No:-10.18231