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Indian Journal of Pathology and Oncology

Spectrum of Surgical management of giant neurofibroma in soft tissue: a single-center prospective analysis in Malwa region: central India

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Author Details: Arun Prakash Dwivedi, Deepak Agrawal, Sanjay M. Desai, D.Y. Mehta, Mayank Pancholi

Volume : 3

Issue : 1

Online ISSN : 2394-6792

Print ISSN : 2394-6784

Article First Page : 19

Article End Page : 22


Neurofibroma, a common benign soft tissue tumor may continue to grow and may attain giant size. We prospectively analyzed surgical management of 10 patients with giant neurofibroma in our medical college from Oct- 2014 to Oct- 2015. The tumors were located in the head and neck (n = 2), limbs (n = 5), and retroperitoneal (n = 2), perineal region (n=1). According to the location and extent of the lesion, surgical management was performed to resect the tumor and wounds were closed either by skin flap or by skin graft. One patient of giant tumor in the esophagus was subjected to wide excision and primary repair. Post surgery the appearance of the patients and also the function of the limbs improved remarkably. In cases of giant neurofibromas, surgical treatment effectively reduces the tumor burden, rehabilitates the appearance, function and so improves the quality of life. Regular follow up and self examination of operated limb helps to diagnose early recurrence.

Keywords: Neurofibroma, Giant neurofibroma, Benign, operation, wide excision