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Indian Journal of Pathology and Oncology


Diagnostic significance of thrombocytopenia in malaria and its correlation with type and severity of malaria


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Author Details: Lal Pranay Singh, S.K. Nema, Sanjeev Narang

Volume : 3

Issue : 2

Online ISSN : 2394-6792

Print ISSN : 2394-6784

Article First Page : 194

Article End Page : 196


Abstract

Background: The malaria is a complex disease which present with fever but brings many pathological changes in all the tissues including hematological changes. The studies have found besides anemia. The qualitative and quantitative changes in leukocytes and platelets are significant and may be used as presumptive markers in a symptomatic smear negative cases. These features will be more useful in endemic areas and during epidemics of disease.
Material and Methods: In the study we have studied hematological parameters with emphasis on platelets counts in cases of malaria. Out of 150 cases, The malaria was confirmed in 100 cases by smear as well as, Immunochromatography test (ICT). The thrombocytopenia and other hematological anomalies were recorded and analyzed.
Result: The study revealed 75% of malaria positive cases had thrombocytopenia which was more severe in cases of P. falcifarum.
Conclusion: Thrombocytopenia showed a statistically significant correlation with malarial infection. Our study stresses the importance of thrombocytopenia and its correlation with type and severity of malaria.

Key Words:
Thrombocytopenia, Plasmodiam vivax. plasmodiam falciparum Immunochromatography test (ICT)