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Indian Journal of Pathology and Oncology

Cervical PAP Smear Examination in Women Living with HIV-A study of 60 cases

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Author Details: Vijayashree Shivappa Neeravari, Anirudha Vasantacharya Kushtagi, Doddappa Mallappa Bannigidad

Volume : 3

Issue : 2

Online ISSN : 2394-6792

Print ISSN : 2394-6784

Article First Page : 264

Article End Page : 267


Cervical cancer in women living with Human Immunodeficiency Virus (HIV) is a major health problem accounting for 26.1-43.8% of all cancers in Indian Women. Women infected with HIV have a higher risk of developing cervical intraepithelial neoplasms. Dysplasia has been reported in 15 to 64.6% of HIV infected women & these rates are 10-12 times higher than those observed among HIV negative women 13%.
Materials and Methods: The aim of this study is to estimate the frequency of abnormal Papanicolau (Pap) smears and mainly to detect precancerous & cancerous lesions as well as inflammatory lesions in HIV-infected women.
Results:  Total 68 samples were collected. Pap smear abnormalities included LSIL(10.2%). HSIL(4.4%), ASCUS(8.8%), ASC-H(2.9%), Carcinoma(1.4%), Specific Infections 33.8% (Bacterial Vaginosis-19.1%, Trichomonas Vaginalis-5.8%, Candidiasis-5.8%, Herpes Simplex-2.9% Cytolytic smear-1.4%), Non-specific Inflammatory smear (36.7%).
Conclusion: In view of high percentage of inflammatory Pap smears, infections and cervical intraepithelial lesions among HIV positives women. Among the various intraepithelial lesions LSIL was the commonest, stressing the need for routine pap smear testing annually in women living with HIV.

HIV, Pap smear, patient living with HIV, Cervical intraepithelial neoplasia