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Indian Journal of Pathology and Oncology


A histopathologic study of 50 nephrectomy specimens


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Author Details: Mahjabeen Salma, Tazyeen Kouser, Mohammed Abdul Nasar

Volume : 3

Issue : 3

Online ISSN : 2394-6792

Print ISSN : 2394-6784

Article First Page : 421

Article End Page : 426


Abstract

Background: The study of Nephrectomy specimens makes an interesting subject. Not only many clinical suspicions are confirmed but also many unsuspecting lesions are brought to light by the Histopahological study.
Objective: To study the histopathology of 50 nephrectomy specimen
Methods: The present study included retrospective analysis of two years (January 2011 – December 2012) and prospective study of two years and three months (January 2013 – March 2014) of Nephrectomy specimens from the records of Department of Pathology, Dr. V. R. K. Women’s Medical College, and Hyderabad. There were 50 nephrectomy specimens of which 39 were non-neoplastic and 11 were neoplastic.
Results: Lesions are more in number in males (31) than in females (19). Non-Neoplastic lesions are more common on Left side (58.98%). The neoplastic lesions are more common on Right side (63.64%). 4 cases of clear cell carcinoma were seen with large cells with abundant clear cytoplasm, centrally located vesicular nucleus with 1 (14.28%) showing nucleoli under low power (Fuhrmans nucleolar grade 3), 2(28.57) showing nucleoli under high power: (Fuhrman nucleolar grade 2) and one (14.28%) with bizarre nucleoli – (Grade 4).
Conclusion: Among the 50 nephrectomy specimens 39 (78%) revealed non-neoplastic lesions and 11 (22%) revealed neoplastic lesions. The lesions were more in males (31) than in females (19). Chronic pyelonephritis was the commonest lesion noted.

Key words:
Nephrectomy specimens, Neoplastic lesions, Chronic pyelonephritis