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Indian Journal of Pathology and Oncology


The histopathological spectrum of meningeal neoplasms


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Author Details: Nitin Maheshvar Gadgil, Sangita Ramulu Margam, Chetan Sudhakar Chaudhari, Prashant Vijay Kumavat

Volume : 3

Issue : 3

Online ISSN : 2394-6792

Print ISSN : 2394-6784

Article First Page : 432

Article End Page : 436


Abstract

Background: Meningiomas are slow-growing and benign tumor of the meninges, which line the skull and enclose the brain.
Methods: We have studied 324 cases of meningeal lesions (clinically diagnosed and histologically proved) in Department of Pathology of a tertiary care hospital. We evaluated its frequency, age and sex distribution and documented as per the WHO histological grade of meningioma.
Results: The commonest age group affected was 41-60 years. Female predominance was seen. Headache being most common symptom with commonest site was intracranial (88.2%). The meningeal lesions consisted of meningioma (96.6%) and non-meningioma lesions (3.4%). The commonest histopathological type of mengioma was transitional (24.2%) followed by meningotheliomatous (22.8%). The 85.6% of the meningioma was WHO Grade I tumor. For WHO Grade II meningiomas, mitotic figures and high cellularity was helpful to diagnose the tumors. The non-meningioma lesions included hemangiopericytoma, solitary fibrous tumor, malignant melanoma and metastasis by carcinoma breast, lung and thyroid.
Conclusion: From our study, we can conclude that benign meningiomas WHO grade I are most common. Intracranial location is the most common for meningioma. Middle-aged group of 41–60 years was predominently affected and it is uncommon in children.

Keywords:
Meningeal neoplasms, Meningioma, WHO grade