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Indian Journal of Pathology and Oncology


A histomorphological study of the neoplastic polypoidal masses of the nasal cavity, paranasal sinuses, and nasopharynx


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Author Details: Radha RK, Prakash CJ, Kavya Bharathidasan

Volume : 4

Issue : 1

Online ISSN : 2394-6792

Print ISSN : 2394-6784

Article First Page : 39

Article End Page : 44


Abstract

Introduction: Mass in the nasal cavity is a fairly common finding in clinical practice. A wide array of neoplastic and non-neoplastic conditions present as a mass in the nasal cavity, paranasal sinuses and nasopharynx. Clinically, it can be quite difficult to distinguish between simple nasal polyps, polypoidal lesions due to specific diseases, and polypoidal neoplasms. Hence histopathological examination of all nasal polyps is very important to arrive at a specific diagnosis and appropriate treatment.
Purpose: The aim of this study was to analyze the histopathological patterns of polypoidal lesions in the nose, paranasal sinuses, and nasopharynx.
Methods: The study was carried out retrospectively from June 2009 to June 2011 and continued prospectively for a period of one year from June 2011 to June 2012 .The retrospective cases were taken from records of the pathology department of a tertiary care hospital. The blocks were re-cut and sections were stained using hematoxylin and eosin. Special staining was done whenever necessary depending on the lesion and studied microscopically.
Observations and Results: A total of 100 cases presented as polypoidal lesions of nose and paranasal sinuses. Out of the 100 polypoidal masses, 42 were diagnosed as neoplasms among which 28 cases were benign and 14 cases were malignant. The benign spectrum included angiofibroma, inverted papilloma, capillary hemangioma and pyogenic granuloma. Malignant cases included mostly squamous cell carcinoma followed by poorly differentiated carcinoma, adenocarcinoma and a single case of plasmacytoma.
Conclusion: Polypoidal masses in the nasal cavity, paranasal sinuses, and nasopharynx represent a large variety of neoplastic lesions of benign and malignant pathologies.

Keywords:
Polypoidal lesions; Nasal polyp; Nasal and paranasal sinuses; Nasopharynx; Nasal neoplasm