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Indian Journal of Pathology and Oncology


Morphological spectrum of peripheral lymphadenopathy – A hospital based study


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Author Details: Suba G., Jayaprakash H.T., Shradha A.

Volume : 4

Issue : 2

Online ISSN : 2394-6792

Print ISSN : 2394-6784

Article First Page : 278

Article End Page : 281


Abstract

Background: Lymphnode is one of the commonest site for neoplastic and non-neoplastic diseases. This study was undertaken to analyse the patterns of lesions seen in peripheral lymphadenopathy cases.
Materials and Method: This retrospective study of 103 cases of lymphnode biopsies was carried out in the department of pathology for a period of 3 years. Relevant patient data were retrieved from the file. Slides were reviewed thoroughly and special stains were applied wherever necessary.
Results: Out of 103 cases, 88 (85.4%) were non-neoplastic lesions and 15 (14.6%) were neoplastic lesions. The most commonly biopsied group was cervical nodes. Tuberculosis was the most common condition 44 cases (42.7%) followed by reactive hyperplasia 41 cases (39.8%). Of the 15 cases (14.6%) of malignancy, 10 (9.7%) were metastatic deposits and 5 (4.9%) were lymphomas.
Conclusion: Tuberculosis is the leading cause of lymphadenopathy and young females are commonly affected. Histopathology is the gold standard in confirming the diagnosis of lymphnode lesions.

Keywords:
Lymphnode, Lymphoma, Neoplastic, Tuberculosis