Indian Journal of Pathology and Oncology

Histopathological pattern of pediatric renal disease – our experience at Kamineni Hospitals, Hyderabad

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Author Details: E. Jayashankar, P. Shailaja, PN Jikki, T. Ramamurti, AK Deshpande

Volume : 4

Issue : 4

Online ISSN : 2394-6792

Print ISSN : 2394-6784

Article First Page : 575

Article End Page : 579


 Introduction: Renal biopsies are very important in diagnosing and managing children with renal diseases. There are few studies which highlight the histological pattern of renal diseases in pediatric age group.
Objective: This study was conducted to analyse indications for renal biopsies, and also histological pattern of renal diseases in children which were referred to the Pathology department, Kamineni Hospitals, Hyderabad by the Nephrology department, Government General Hospital, Kurnool.
Materials and Method: A retrospective analysis of kidney biopsy reports from December 2013 to December 2016 was done. Adult biopsies, inadequate and renal allograft biopsies were excluded from the study. Only pediatric age group of 1-14 years was considered.
Results: Out of total 750 biopsies, 130 cases belong to pediatric age group. Male to female ratio is 1.8:1, with a mean age of 10 + of -4. Nephrotic syndrome is the most common indication for renal biopsies and histologically minimal change disease (MCD) is the most common (43%) histological pattern followed by membranoproliferative glomerulonephritis (MPGN) (18%), focal segmental glomerulosclerosis (FSGS) (11%), and Post infectious glomerulonephritis PIGN (10%) etc.
Conclusion: Nephrotic syndrome is the most common indication for renal biopsies and MCD is the most common type of glomerulonephritis among pediatric cases diagnosed at our institution.