Indian Journal of Pathology and Oncology

An autopsy case report on OEIS Complex

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Author Details: Hadiya Naureen, Ashwini HN

Volume : 4

Issue : 4

Online ISSN : 2394-6792

Print ISSN : 2394-6784

Article First Page : 664

Article End Page : 666


OEIS complex is a rare congenital anomaly characterised by omphalocele, exstrophy of bladder, imperforate anus and spinal defects. It is a defect that affects the midline of the lower inferior body. This condition is mostly fatal and almost incompatible with life. A diabetic multiparous woman with history of previous 2 spontaneous abortions presented with 3rd pregnancy, spontaneously delivered a dead fetus of 17weeks gestational age. Here we present an autopsy case report of a 17 weeks fetus with features of OEIS complex which had the above mentioned features along with left club foot, absence of spleen, pancreas & both internal and external genitalia. Microscopic examination of the placenta showed villi with fibrin clot deposition and calcification suggesting that feto-maternal insufficiency of placenta was the cause of death.

OEIS complex, Omphalocele, Exstrophy of bladder, Club foot, Myelomeningocele