Indian Journal of Pathology and Oncology

Pure Yolk Sac Tumour of Postpubertal-type- A rare occurrence

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Author Details: Linda Lamngaiching Changsan, Utpal Dutta, Projnan Saikia, Swagata Dowerah

Volume : 4

Issue : 4

Online ISSN : 2394-6792

Print ISSN : 2394-6784

Article First Page : 670

Article End Page : 673


Introduction: The most common form of testicular neoplasm in prepubertal children is Yolk sac tumour, occurs mostly in the pure form. However, in adults, it is invariably found admixed with other germ cell tumour components.
Case Report: A 22-years-old male presented to surgery OPD with abdominal pain for 1 month and on examination, was found to have bilateral cryptorchidism with a swelling on the left iliac fossa. The left testis was resected and was sent for histopathological examination. Microscopy revealed picture of yolk sac tumour and the tissue was again thoroughly sampled to find out other components of a mixed GCT. As none was found and a diagnosis of pure yolk sac tumor, postpubertal-type was made based on morphological features. Immunohistochemistry showed focal positivity for alpha-fetoprotein and CD30 negativity.
Conclusion: This case of pure yolk sac tumour, postpubertal-type has been reported in view of its rarity and its aggressive nature compared to its prepubertal counterpart. However, diagnosis of these tumours should only be given after proper extensive sectioning to rule out any other germ cell component.

Yolk sac tumor, Postpubertal-type, Germ cell tumour, Cryptorchidism, Alpha-fetoprotein