Indian Journal of Pathology and Oncology

A varied morphological spectrum of urinary bladder carcinoma - A rare diagnostic entity

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Article Type : Case Report

Author Details: N Sadiya*,Natarajan Sezhian,Mitra Ghosh,Deepak Lamech

Volume : 6

Issue : 2

Online ISSN : 2394-6792

Print ISSN : 2394-6784

Article First Page : 331

Article End Page : 335


Bladder carcinoma is the seventh most common malignancy worldwide and multiple risk factors have been linked to bladder cancer. Urothelial carcinoma accounts for the most common histological subtype and has a propensity for divergent differentiation. The clinical outcome of some of the variants differs from the typical urothelial carcinoma and recognition of these variants is pertinent. Primary small cell carcinoma is an extremely rare malignant neoplasm which accounts for less than 1% of urinary bladder cancer. We present two cases of bladder carcinoma in elderly men with varied histomorphological subtypes which posed a diagnostic challenge.

Keywords: Bladder carcinoma, Primary small cell carcinoma, Hypercalcemia, High grade urothelial carcinoma, Glandular differentiation.

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