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Indian Journal of Pharmacy and Pharmacology


Gabapentin as a Novel Drug


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Author Details: Semira

Volume : 2

Issue : 4

Online ISSN : 2393-9087

Print ISSN : 2393-9079

Article First Page : 226

Article End Page : 229


Abstract

Background: Gabapentin is an antiepileptic and analgesic drug. There is an urge for reliable scientific evidence to support its ongoing widespread use for treatment of a number of other conditions as well.
Objective: Critical appraisal of the available literature on pharmacological basis of approved and off-label uses of gabapentin to assess the scope for its new roles in therapeutics.
Data Source: A systematic review of literature was made to study history, pharmacology, approved uses and off-label uses of gabapentin.
Conclusion: Gabapentin use has extended into the management of a variety of disorders besides epilepsy, neuropathic pain and restless leg syndrome. A large number of clinical trials are conducted to establish its role in a wide spectrum of clinical situations. While tremendous scientific speculations are surrounding the drug; there is a need to know more about this novel drug including its mechanism of action and adverse effect profile.

Key words:
Gabapentin, off-label, anticonvulsant