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Indian Journal of Pharmacy and Pharmacology


Phytochemical and In-Vitro Evaluation of Antioxidant Activity of Sesamum Indicum Leaves


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Author Details: Vani K, Malathi Priyanka M, Durga Srinivas P, Naveen Kumar U, Kalyani Y, Aminabee SK, Lakshmana Rao

Volume : 3

Issue : 1

Online ISSN : 2393-9087

Print ISSN : 2393-9079

Article First Page : 7

Article End Page : 12


Abstract

Objective: The aim of the present study was to evaluate preliminary phytochemicals and in-vitro evaluation of antioxidant activity of Sesamum indicum leaves.
Methods: Antioxidant activity was evaluated by using in-vitro antioxidant assay models like hydrogen peroxide scavenging activity, reducing power assay and phosphomolybdenum method. All the antioxidant activities were compared with standard antioxidant such as ascorbic acid.
Results: The ethanolic extract of Sesamum indicum leaves was found to contain flavonoids. Additionally, the capacity to scavenge hydrogen peroxide, the reducing power (capacity to reduce Fe3+ to Fe2+) and formation of phosphomolybdenum complex were evaluated. From this study it was concluded that the extract exhibited a concentration dependent scavenging activity.

Keywords:
Sesamum indicum, Flavonoids, Hydrogen peroxide scavenging, Reducing power, Phosphomolybdenum complex