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Journal of Pharmaceutical and Biological Sciences


Chemical constituents from the Aerial parts of Rumex hastatus D. Don


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Author Details: Shahnaz Sultana, Mohammed Ali, Showkat Rasool Mir

Volume : 5

Issue : 5

Online ISSN : 2320-1924

Print ISSN :

Article First Page : 179

Article End Page : 187


Abstract

Rumex hastatus D. Don (Polygonaceae) occurs in Afghanistan, Pakistan, India, Bhutan and western China as a small perennial shrub and is used as an alternative, astringent, carminative, diuretic, laxative, tonic and to treat bloody dysentery, bilious complaints, blood pressure, cough, diarrhoea, dysentery, fevers, jaundice, headache, lung bleeding, piles, neoplasm, rheumatism, skin diseases, wounds and throat pain. Phytochemical investigation of a methanolic extract of the leaves led to isolate seven new chemical constituents characterized as 3′,4′-dihydroxybenzyl oleate (2), β-sitosterol 3-benzyl ether 3′-capriate (4), β-sitosterol 3-benzyl ether 3′-oleate (5), β-sitosterol 3-(3′,4′-dihydroxybenzyl) ether 3′-linoleate (6), β-sitosterol-3β-benzyl 3′-oxy-3′-O-β-D-galactopyranosyl-(6a→1b)-O-β-D-galactopyranosyl-(6b→1c)-O-β-D-galactopyranosyl-(6c→1d)-O-β-D-galactopyranosyl-2d-capriate (β-sitosterol 3-(3′-hydroxybenzyl) 3′-O-β-D-tetragalactoside 2d-capriate, 7), 1-undecanoxy-3-phenol-3-O-β-D-xylopyranosyl-(2a→1b)- O-β-D-xylopyranosyl-(2b→1c)- O-β-D-xylopyranosyl-(2c→1d)- O-β-D-xylopyranosyl-(2d→1e)- O-β-D-xylopyranoside (n-undecanoxyphenol 3-O-β-D-pentaxyloside, 8) and α-L-glucopyranosyl-(2a→1b)-O-α-L-glucopyranosyl-(2b→1c)-O-α-L-glucopyranosyl-(2c→1d)-O-α-L-gluco- pyranosyl -(2d→1e)-O- α-L -glucopyranosyl-(6e→1f)-O- α-L –glucopyranoside (α-L-hexaglucoside, 9) together with the known compounds tridecyl oleate (1) and β-sitosteryl linoleate (3). The structures of all the isolated phytoconstituents have been established on the basis of spectral data analysis and chemical reactions.

Keywords:
Rumex hastatus, Aerial parts, Chemical constituents, Isolation, Structures elucidation

Doi No:-10.18231