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Panacea Journal of Medical Sciences


Clinico-laboratory Profile of Hypothyroidism with Emphasis on Cardiovascular Manifestations


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Author Details: Vairamanikandan, P Sathyamurthy, M Rajkumar, Vaasanthi

Volume : 6

Issue : 2

Online ISSN : 2348-7682

Print ISSN : 2249-8176

Article First Page : 59

Article End Page : 65


Abstract

Hypothyroidism is a highly prevalent endocrine disorder. Hypothyroidism affects almost all organs of the body, the cardiovascular system being the most sensitive one. There has been an increased usage of biochemical tests for screening of hypothyroidism. We have studied the clinical and laboratory profile of hypothyroid patients with particular emphasis on their cardiovascular manifestations. 50 patients of hyperthyroidism were included in the study. Patients with other co-morbidities which could contribute to cardiovascular manifestations were excluded from the study. In this study Females (60%) were more than males (40%), commonest general presenting symptoms were fatigue (52%) and weight gain (48%), commonest cardio vascular symptoms were palpitation (78%), followed by dyspnoea (26%) and chest pain (4%), commonest cardio vascular signs were found to be tachycardia (82%), widened pulse pressure (50%) and pedal edema (12%), commonest ECG finding was found to be Sinus tachycardia(46%) followed by atrial Fibrillation(28%), Non-Specific ST-T changes, Left Ventricular Hypertrophy, RV hypertrophy and RBBB. Systolic dysfunction and Chamber enlargement (18%) were the more prevalent echo manifestations. This study shows that because of their high prevalence and constant nature, clinical symptoms and signs of hypothyroidism cannot be over looked for screening and clinical diagnosis. Also the cardiovascular manifestations being increasingly prevalent should be routinely screened in all hypothyroid patients.

Keywords:
Hypothyroidism, Clinical profile, Cardiovascular manifestation