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Santosh University Journal of Health Sciences


Study of Pulmonary Function Test and Oxidative Stress Marker in Chronic Obstructive Pulmonary (COPD) Patients


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Author Details: Ranjana, Jyoti Batra, Yogesh Tripathi, Sudeep Kumar

Volume : 1

Issue : 2

Online ISSN : 2455-1732

Print ISSN :

Article First Page : 65

Article End Page : 67


Abstract

 Background: Chronic Obstructive Pulmonary Disease (COPD) is a health problem with increasing severity, as exposure to risk factors such as cigarette smoke, pollution is inevitable. Oxidant antioxidant imbalance cause oxidative burden leading to lung tissue damage.
Aims and Objective: The aim of present study was to evaluate oxidative stress marker (MDA) and Lung function test COPD patients.
Materials and Methods: MDA level were estimated by thiobarbituric acid method.
Result: Serum mean level of MDA was significantly higher in COPD patients as compared to normal healthy individual. FEV1 andFEV1/FVC ratio significantly decreased in COPD patients as compared to control.
Conclusion: Increased MDA level indicate excess of oxidative stress in COPD patients. Dietary supplementation of antioxidantto COPD patients is strongly recommended.

Keywords:
MDA, Oxidative Stress, COPD, FVC, FEV1