Short term results of platelet rich plasma in early stages of osteoarthritis knee
Introduction: Osteoarthritis of knee is a most common form of arthritis spread rampantly today. Platelet-rich plasma injections enhance cartilage repair and relieve osteoarthritis Symptoms. Thus it delays the need for joint replacement.
Objective: To investigate the effect of platelet-rich plasma (PRP) on progression of early stages of osteoarthritis knee.
Methodology: A case series study of 50 patients was carried out. Results were analyzed on the basis of following scores:
Ø WOMAC (Western Ontario and McMaster Universities Osteoarthritis Index)
Ø KSS (Knee Society Score)
Ø VAS (Visual Analogue Scale)
Results: There were no significant adverse event observed. Statistically significant results in the Western Ontario and McMaster Universities Osteoarthritis Index and KSS and VAS scorings were recorded in patients who received PRP injections after a 3 and 6 months follow up.
Conclusions: Our study suggests that autologous PRP can be used as an effective and safe method in the treatment of the early stages of osteoarthritis. But further studies are needed to confirm these finding and to investigate the long term effects of autologous PRP.
Keywords: Autologous PRP, Osteoarthritis knee